Analysis of Serum Paraoxonase 1 Using Mass Spectrometry and Lectin Immunoassay in Patients With Alpha-Fetoprotein Negative Hepatocellular Carcinoma

Analysis of Serum Paraoxonase 1 Using Mass Spectrometry and Lectin Immunoassay in Patients With Alpha-Fetoprotein Negative Hepatocellular Carcinoma

The diagnosis of AFP (alpha-fetoprotein)-negative HCC (hepatocellular carcinoma) mostly relies on imaging and pathological examinations, and it lacks valuable and practical markers. Protein N-glycosylation is a crucial post-translation modifying process related to many biological functions in an org...

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Bibliographic Details
Main Authors: Xinyi Cao, Zhao Cao, Yuyin Shao, Chao Liu, Guoquan Yan, Xinmin Meng, Lei Zhang, Chen Chen, Guiyue Huang, Hong Shu, Haojie Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
alpha-fetoprotein-negative hepatocellular carcinoma
PON1
biomarker
glycoproteomics
mass spectrometry
lectin ELISA
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.651421/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.651421/full

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