Heparin-Mimicking Polymer-Based In Vitro Platform Recapitulates In Vivo Muscle Atrophy Phenotypes

Heparin-Mimicking Polymer-Based In Vitro Platform Recapitulates In Vivo Muscle Atrophy Phenotypes

The cell–cell/cell–matrix interactions between myoblasts and their extracellular microenvironment have been shown to play a crucial role in the regulation of in vitro myogenic differentiation and in vivo skeletal muscle regeneration. In this study, by harnessing the heparin-mimicking polymer, poly(s...

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Bibliographic Details
Main Authors: Hyunbum Kim, Ji Hoon Jeong, Mona Fendereski, Hyo-Shin Lee, Da Yeon Kang, Sung Sik Hur, Jhaleh Amirian, Yunhye Kim, Nghia Thi Pham, Nayoung Suh, Nathaniel Suk-Yeon Hwang, Seongho Ryu, Jeong Kyo Yoon, Yongsung Hwang
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
synthetic mimic of heparin
poly(sodium-4-styrenesulfonate)
myoblast
myogenic differentiation
fusion
focal adhesion kinase (FAK)
Online Access:https://www.mdpi.com/1422-0067/22/5/2488

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https://www.mdpi.com/1422-0067/22/5/2488

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