SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization

SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization

Summary: Transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from humans to farmed mink has been observed in Europe and the US. In the infected animals, viral variants arose that harbored mutations in the spike (S) protein, the target of neutralizing antibodies, and these va...

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Bibliographic Details
Main Authors: Markus Hoffmann, Lu Zhang, Nadine Krüger, Luise Graichen, Hannah Kleine-Weber, Heike Hofmann-Winkler, Amy Kempf, Stefan Nessler, Joachim Riggert, Martin Sebastian Winkler, Sebastian Schulz, Hans-Martin Jäck, Stefan Pöhlmann
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Cell Reports
Subjects:
SARS-CoV-2
spike protein
mink
mutation
variant
Y453F
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721003314

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http://www.sciencedirect.com/science/article/pii/S2211124721003314

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