Contribution of the Ly49E natural killer receptor in the immune response to Plasmodium berghei infection and control of hepatic parasite development.

Natural killer (NK) cells have different roles in the host response against Plasmodium-induced malaria depending on the stage of infection. Liver NK cells have a protective role during the initial hepatic stage of infection by production of the TH1-type cytokines IFN-γ and TNF-α. In the subsequent e...

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Main Authors: Jessica Filtjens, Lander Foquet, Sylvie Taveirne, Els Van Ammel, Mandy Vanhees, Aline Van Acker, Tessa Kerre, Tom Taghon, Bart Vandekerckhove, Jean Plum, Philippe E Van den Steen, Georges Leclercq
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3907506?pdf=render