Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol

The lipid composition of cellular membranes is regulated to maintain membrane fluidity. A key enzyme involved in this process is the membrane-bound stearoyl-CoA desaturase (SCD) which is the rate-limiting enzyme in the cellular synthesis of monounsaturated fatty acids from saturated fatty acids. A p...

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Bibliographic Details
Main Author: James M. Ntambi
Format: Article
Language:English
Published: Elsevier 1999-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520334015