Regulatory Snapshots: integrative mining of regulatory modules from expression time series and regulatory networks.

Explaining regulatory mechanisms is crucial to understand complex cellular responses leading to system perturbations. Some strategies reverse engineer regulatory interactions from experimental data, while others identify functional regulatory units (modules) under the assumption that biological syst...

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Bibliographic Details
Main Authors: Joana P Gonçalves, Ricardo S Aires, Alexandre P Francisco, Sara C Madeira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3341384?pdf=render