Zebrafish model of KRAS-initiated pancreatic endocrine tumor

Pancreatic cancer constitutes a genetic disease in which somatic mutations in the KRAS proto-oncogene are detected in 95% of cases. Activation of the KRAS proto-oncogene represents an initiating event in pancreatic tumorigenesis. Here, we established a zebrafish pancreatic neoplasia model that recap...

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Bibliographic Details
Main Authors: Sekyung Oh, Joon Tae Park
Format: Article
Language:English
Published: Taylor & Francis Group 2019-05-01
Series:Animal Cells and Systems
Subjects:
Online Access:http://dx.doi.org/10.1080/19768354.2019.1610058