Cyclooxygenase/lipoxygenase shunting lowers the anti-cancer effect of cyclooxygenase-2 inhibition in colorectal cancer cells

Cyclooxygenase/lipoxygenase shunting lowers the anti-cancer effect of cyclooxygenase-2 inhibition in colorectal cancer cells

<p>Abstract</p> <p>Background</p> <p>Arachidonic acid metabolite, generated by cyclooxygenase (COX), is implicated in the colorectal cancer (CRC) pathogenesis. Inhibiting COX may therefore have anti-carcinogenic effects. Results from use of non-steroidal anti-inflammato...

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Bibliographic Details
Main Authors: Ganesh Radhakrishnan, Marks Daniel JB, Sales Kevin, Winslet Marc C, Seifalian Alexander M
Format: Article
Language:English
Published: BMC 2012-09-01
Series:World Journal of Surgical Oncology
Subjects:
Apoptosis
Colorectal cancer
Cyclooxygenase
Eicosanoids
Lipoxygenase
Online Access:http://www.wjso.com/content/10/1/200

Internet

http://www.wjso.com/content/10/1/200

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