Exogenous interferon-alpha and interferon-gamma increase lethality of murine inhalational anthrax.

Bacillus anthracis, the etiologic agent of inhalational anthrax, is a facultative intracellular pathogen. Despite appropriate antimicrobial therapy, the mortality from inhalational anthrax approaches 45%, underscoring the need for better adjuvant therapies. The variable latency between exposure and...

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Bibliographic Details
Main Authors: Jeffrey A Gold, Yoshihiko Hoshino, Marcus B Jones, Satomi Hoshino, Anna Nolan, Michael D Weiden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1937023?pdf=render