Two Variants in the NOTCH4 and HLA-C Genes Contribute to Familial Clustering of Psoriasis

Psoriasis is a multifactorial immune-mediated skin disease with a strong genetic background. Previous studies reported that psoriasis with a family history (PFH) and sporadic psoriasis (SP) have a distinct manifestation and genetic predisposition. However, the genetic heterogeneity of PFH and SP in...

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Bibliographic Details
Main Authors: Minglong Cai, He Huang, Zhulin Hu, Tao Yuan, Weiran Li, Yaoguang Liu, Lijun Zheng, Yan Zhang, Yujun Sheng, Xuejun Zhang
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2020/6907378