Grasp55 −/− mice display impaired fat absorption and resistance to high-fat diet-induced obesity

The physiological roles of the Golgi reassembly-stacking protein 55 (GRASP55/GORASP55) remain largely elusive. Here, the authors show that the Golgi-resident protein GRASP55 plays a crucial role in lipid homeostasis by regulating intestinal lipid uptake.

Bibliographic Details
Main Authors: Jiyoon Kim, Hyeyon Kim, Shin Hye Noh, Dong Geon Jang, Shi-Young Park, Dongkook Min, Hyunki Kim, Hee-Seok Kweon, Hoguen Kim, Sowon Aum, Sookyung Seo, Cheol Soo Choi, Hail Kim, Jae Woo Kim, Seok Jun Moon, Heon Yung Gee, Min Goo Lee
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14912-x