Inflammation and skin cholesterol in LDLr−/−, apoA-I−/− mice: link between cholesterol homeostasis and self-tolerance?

Diet-fed low density lipoprotein receptor-deficient/apolipoprotein A-I-deficient (LDLr−/−, apoA-I−/−) mice accumulate a 10-fold greater mass of cholesterol in their skin despite a 1.5- to 2-fold lower plasma cholesterol concentration compared with diet-fed LDLr−/− mice. The accumulation of cholester...

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Bibliographic Details
Main Authors: Manal Zabalawi, Manish Bharadwaj, Heather Horton, Mark Cline, Mark Willingham, Michael J. Thomas, Mary G. Sorci-Thomas
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520436363