The role of cellular reactive oxygen species in cancer chemotherapy

The role of cellular reactive oxygen species in cancer chemotherapy

Abstract Most chemotherapeutics elevate intracellular levels of reactive oxygen species (ROS), and many can alter redox-homeostasis of cancer cells. It is widely accepted that the anticancer effect of these chemotherapeutics is due to the induction of oxidative stress and ROS-mediated cell injury in...

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Bibliographic Details
Main Authors: Haotian Yang, Rehan M Villani, Haolu Wang, Matthew J Simpson, Michael S Roberts, Min Tang, Xiaowen Liang
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Reactive oxygen species (ROS)
Redox
Cancer
Chemotherapy
ROS detection
Mathematical modeling
Online Access:http://link.springer.com/article/10.1186/s13046-018-0909-x

Internet

http://link.springer.com/article/10.1186/s13046-018-0909-x

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