Cardioprotective effects of microRNA-18a on acute myocardial infarction by promoting cardiomyocyte autophagy and suppressing cellular senescence via brain derived neurotrophic factor

Cardioprotective effects of microRNA-18a on acute myocardial infarction by promoting cardiomyocyte autophagy and suppressing cellular senescence via brain derived neurotrophic factor

Abstract Background The prevention of cardiovascular diseases is a matter of great concern, of which acute myocardial infarction (AMI) remains one of the leading causes of death resulting in high morbidity worldwide. Emerging evidence highlights the importance of microRNAs (miRNAs) as functional reg...

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Bibliographic Details
Main Authors: Bin Lin, Deguang Feng, Jing Xu
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Cell & Bioscience
Subjects:
MicroRNA-18a
Brain derived neurotrophic factor
Acute myocardial infarction
Akt/mTOR axis
Autophagy
Senescence
Online Access:http://link.springer.com/article/10.1186/s13578-019-0297-8

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http://link.springer.com/article/10.1186/s13578-019-0297-8

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