Downregulation of hippocampal NR2A/2B subunits related to cognitive impairment in a pristane-induced lupus BALB/c mice.

Neuropsychiatric systemic lupus erythematosus (NPSLE) is associated with learning and memory deficit. Murine model of lupus induced by pristane in BALB/c mice is an experimental model that resembles some clinical and immunological SLE pathogenesis. Nevertheless, there is no experimental evidence tha...

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Main Authors: Jonatan Luciano-Jaramillo, Flavio Sandoval-García, Mónica Vázquez-Del Mercado, Yanet Karina Gutiérrez-Mercado, Rosa Elena Navarro-Hernández, Erika Aurora Martínez-García, Oscar Pizano-Martínez, Fernanda Isadora Corona-Meraz, Jacinto Bañuelos-Pineda, Jorge Fernando Floresvillar-Mosqueda, Beatriz Teresita Martín-Márquez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217190