Diagnostic and prognostic impact of cytokeratin 18 expression in human tumors: a tissue microarray study on 11,952 tumors

Diagnostic and prognostic impact of cytokeratin 18 expression in human tumors: a tissue microarray study on 11,952 tumors

Abstract Background Cytokeratin 18 (CK18) is an intermediate filament protein of the cytokeratin acidic type I group and is primarily expressed in single-layered or “simple” epithelial tissues and carcinomas of different origin. Methods To systematically determine CK18 expression in normal and cance...

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Bibliographic Details
Main Authors: Anne Menz, Timo Weitbrecht, Natalia Gorbokon, Franziska Büscheck, Andreas M. Luebke, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Doris Höflmayer, Sören Weidemann, Christoph Fraune, Katharina Möller, Christian Bernreuther, Patrick Lebok, Till Clauditz, Guido Sauter, Ria Uhlig, Waldemar Wilczak, Stefan Steurer, Sarah Minner, Eike Burandt, Rainer Krech, David Dum, Till Krech, Andreas Marx, Ronald Simon
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Molecular Medicine
Subjects:
Cytokeratin 18 (CK18)
Tissue microarray
Immunohistochemistry
Online Access:https://doi.org/10.1186/s10020-021-00274-7

Internet

https://doi.org/10.1186/s10020-021-00274-7

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