An advanced enrichment method for rare somatic retroelement insertions sequencing

An advanced enrichment method for rare somatic retroelement insertions sequencing

Abstract Background There is increasing evidence that the transpositional activity of retroelements (REs) is not limited to germ line cells, but often occurs in tumor and normal somatic cells. Somatic transpositions were found in several human tissues and are especially typical for the brain. Severa...

Full description

Bibliographic Details
Main Authors: Alexander Y. Komkov, Anastasia A. Minervina, Gaiaz A. Nugmanov, Mariia V. Saliutina, Konstantin V. Khodosevich, Yuri B. Lebedev, Ilgar Z. Mamedov
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Mobile DNA
Subjects:
Somatic retroelement insertions
Genomic normalization
Kamchatka Crab duplex-specific nuclease
Online Access:http://link.springer.com/article/10.1186/s13100-018-0136-1

Internet

http://link.springer.com/article/10.1186/s13100-018-0136-1

Similar Items