Down-regulation of the cardiac sarcoplasmic reticulum ryanodine channel in severely food-restricted rats

Down-regulation of the cardiac sarcoplasmic reticulum ryanodine channel in severely food-restricted rats

We have shown that myocardial dysfunction induced by food restriction is related to calcium handling. Although cardiac function is depressed in food-restricted animals, there is limited information about the molecular mechanisms that lead to this abnormality. The present study evaluated the effects...

Full description

Bibliographic Details
Main Authors: V.A. Vizotto, R.F. Carvalho, M.M. Sugizaki, A.P. Lima, F.F. Aragon, C.R. Padovani, A.V.B. Castro, M. Dal Pai-Silva, C.R. Nogueira, A.C. Cicogna
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2007-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Food restriction
SERCA2
Ryanodine channel
Phospholamban
mRNA
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000100004

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000100004

Similar Items