Altered PGE2-EP2 is associated with an excessive immune response in HBV-related acute-on-chronic liver failure

Altered PGE2-EP2 is associated with an excessive immune response in HBV-related acute-on-chronic liver failure

Abstract Background and aims Prostaglandin E receptor 2 (EP2) is an immune modulatory molecule that regulates the balance of immunity. Here we investigated the role of EP2 in immune dysregulation in patients with acute-on-chronic liver failure (ACLF). Methods Plasma Progstaglandin E2 (PGE2) levels a...

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Bibliographic Details
Main Authors: Yunyun Wang, Chao Chen, Jinjin Qi, Fengtian Wu, Jun Guan, Zhi Chen, Haihong Zhu
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Translational Medicine
Subjects:
ACLF
PGE2
EP2
Systemic inflammation
Online Access:http://link.springer.com/article/10.1186/s12967-019-1844-0

Internet

http://link.springer.com/article/10.1186/s12967-019-1844-0

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