Downregulation of BTLA on NKT Cells Promotes Tumor Immune Control in a Mouse Model of Mammary Carcinoma

Downregulation of BTLA on NKT Cells Promotes Tumor Immune Control in a Mouse Model of Mammary Carcinoma

Natural Killer T cells (NKT cells) are emerging as critical regulators of pro- and anti-tumor immunity, both at baseline and in therapeutic settings. While type I NKT cells can promote anti-tumor immunity, their activity in the tumor microenvironment may be limited by negative regulators such as inh...

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Bibliographic Details
Main Authors: Divya Sekar, Luisa Govene, María-Luisa del Río, Evelyn Sirait-Fischer, Annika F. Fink, Bernhard Brüne, José I. Rodriguez-Barbosa, Andreas Weigert
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:International Journal of Molecular Sciences
Subjects:
natural killer T cells
inflammation
cancer
Online Access:http://www.mdpi.com/1422-0067/19/3/752

Internet

http://www.mdpi.com/1422-0067/19/3/752

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