Multimodal Tracking of Hematopoietic Stem Cells from Young and Old Mice Labeled with Magnetic–Fluorescent Nanoparticles and Their Grafting by Bioluminescence in a Bone Marrow Transplant Model

Multimodal Tracking of Hematopoietic Stem Cells from Young and Old Mice Labeled with Magnetic–Fluorescent Nanoparticles and Their Grafting by Bioluminescence in a Bone Marrow Transplant Model

This study proposes an innovative way to evaluate the homing and tracking of hematopoietic stem cells from young and old mice labeled with SPION<sub>NIRF-Rh</sub> conjugated with two types of fluorophores (NIRF and Rhodamine), and their grafting by bioluminescence (BLI) in a bone marrow...

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Bibliographic Details
Main Authors: Fernando A. Oliveira, Mariana P. Nucci, Javier B. Mamani, Arielly H. Alves, Gabriel N. A. Rego, Andrea T. Kondo, Nelson Hamerschlak, Mara S. Junqueira, Lucas E. B. de Souza, Lionel F. Gamarra
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
hematopoietic stem cell
nanoparticle
homing
tracking
near-infrared fluorescence imaging
magnetic resonance imaging
Online Access:https://www.mdpi.com/2227-9059/9/7/752

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https://www.mdpi.com/2227-9059/9/7/752

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