Nanocomposite treatment reduces disease and lethality in a murine model of acute graft-versus-host disease and preserves anti-tumor effects.

Graft versus host disease (GVHD) is an immunological disorder triggered by bone marrow transplantation that affects several organs, including the gastrointestinal tract and liver. Fullerenes and their soluble forms, fullerols, are nanocomposites with a closed symmetrical structure with anti-inflamma...

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Bibliographic Details
Main Authors: Priscila T T Bernardes, Bárbara M Rezende, Carolina B Resende, Talles P De Paula, Alesandra C Reis, William A Gonçalves, Elias G Vieira, Maurício V B Pinheiro, Danielle G Souza, Marina G M Castor, Mauro M Teixeira, Vanessa Pinho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395348?pdf=render