Two novel blood-based biomarker candidates measuring degradation of tau are associated with dementia: A prospective study.

Truncated tau appears to be specifically related to disease pathology and recent studies have shown the presence and elevation of several truncated tau species in Cerebrospinal fluid (CSF) of subjects with Alzheimer's disease (AD); however, the relevance of truncated Tau measurements in blood i...

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Bibliographic Details
Main Authors: Jesper Skov Neergaard, Katrine Dragsbæk, Claus Christiansen, Morten Asser Karsdal, Susanne Brix, Kim Henriksen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5895005?pdf=render