Novel insight into mutational landscape of head and neck squamous cell carcinoma.

Novel insight into mutational landscape of head and neck squamous cell carcinoma.

Development of head and neck squamous cell carcinoma (HNSCC) is characterized by accumulation of mutations in several oncogenes and tumor suppressor genes. We have formerly described the mutation pattern of HNSCC and described NOTCH signaling pathway alterations. Given the complexity of the HNSCC, h...

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Bibliographic Details
Main Authors: Daria A Gaykalova, Elizabeth Mambo, Ashish Choudhary, Jeffery Houghton, Kalyan Buddavarapu, Tiffany Sanford, Will Darden, Alex Adai, Andrew Hadd, Gary Latham, Ludmila V Danilova, Justin Bishop, Ryan J Li, William H Westra, Patrick Hennessey, Wayne M Koch, Michael F Ochs, Joseph A Califano, Wenyue Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3965530?pdf=render

Internet

http://europepmc.org/articles/PMC3965530?pdf=render

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