The identification of novel immunogenic antigens as potential Shigella vaccine components

Abstract Background Shigella is a major diarrheal pathogen for which there is presently no vaccine. Whole genome sequencing provides the ability to predict and derive novel antigens for use as vaccines. Here, we aimed to identify novel immunogenic Shigella antigens that could serve as Shigella vacci...

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Bibliographic Details
Main Authors: Ruklanthi de Alwis, Li Liang, Omid Taghavian, Emma Werner, Hao Chung The, Trang Nguyen Hoang Thu, Vu Thuy Duong, D. Huw Davies, Philip L. Felgner, Stephen Baker
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Genome Medicine
Online Access:https://doi.org/10.1186/s13073-020-00824-4