Relationships between oxygen changes in the brain and periphery following physiological activation and the actions of heroin and cocaine

Abstract Using two-sensor electrochemical recordings in freely moving rats, we examined the relationship between physiological and drug-induced oxygen fluctuations in the brain and periphery. Animals chronically implanted with oxygen sensors in the nucleus accumbens (NAc) and subcutaneous (SC) space...

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Bibliographic Details
Main Authors: Shruthi A. Thomas, Carlos M. Curay, Eugene A. Kiyatkin
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85798-y