Conserved motifs in the hypervariable domain of chikungunya virus nsP3 required for transmission by Aedes aegypti mosquitoes.

BACKGROUND:Chikungunya virus (CHIKV) is a re-emerging arthropod-borne (arbo)virus that causes chikungunya fever in humans and is predominantly transmitted by Aedes aegypti mosquitoes. The CHIKV replication machinery consists of four non-structural proteins (nsP1-4) that additionally require the pres...

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Main Authors: Giel P Göertz, Marit Lingemann, Corinne Geertsema, Marleen H C Abma-Henkens, Chantal B F Vogels, Constantianus J M Koenraadt, Monique M van Oers, Gorben P Pijlman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6249005?pdf=render