Cyclosporine A trough concentrations are associated with acute GvHD after non-myeloablative allogeneic hematopoietic cell transplantation.

Cyclosporine A trough concentrations are associated with acute GvHD after non-myeloablative allogeneic hematopoietic cell transplantation.

Low plasma CsA concentrations (<300-350 ng/mL) early following allogeneic hematopoietic stem cell transplantation (HSCT) is associated with an increased risk of developing acute graft-versus-host disease (aGvHD). Nevertheless, the current optimal target trough concentration for CsA following HSCT...

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Bibliographic Details
Main Authors: Elizabeth A de Kort, Heleen S de Lil, Manita E J Bremmers, Lenneke F J van Groningen, Nicole M A Blijlevens, Gerwin Huls, Roger J M Brüggemann, Suzanne van Dorp, Walter J F M van der Velden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213913

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https://doi.org/10.1371/journal.pone.0213913

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