Conserved Autophagy Pathway Contributes to Stress Tolerance and Virulence and Differentially Controls Autophagic Flux Upon Nutrient Starvation in Cryptococcus neoformans

Conserved Autophagy Pathway Contributes to Stress Tolerance and Virulence and Differentially Controls Autophagic Flux Upon Nutrient Starvation in Cryptococcus neoformans

Autophagy is mainly a catabolic process, which is used to cope with nutrient deficiency and various stress conditions. Human environment often imposes various stresses on Cryptococcus neoformans, a major fungal pathogen of immunocompromised individuals; therefore, autophagic response of C. neoforman...

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Bibliographic Details
Main Authors: Xueru Zhao, Weijia Feng, Xiangyang Zhu, Chenxi Li, Xiaoyu Ma, Xin Li, Xudong Zhu, Dongsheng Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Microbiology
Subjects:
Cryptococcus neoformans
ATG genes
autophagy
Atg8
starvation
virulence
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02690/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02690/full

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