Arterial response to shear stress critically depends on endothelial TRPV4 expression.

BACKGROUND: In blood vessels, the endothelium is a crucial signal transduction interface in control of vascular tone and blood pressure to ensure energy and oxygen supply according to the organs' needs. In response to vasoactive factors and to shear stress elicited by blood flow, the endotheliu...

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Bibliographic Details
Main Authors: Veronika Hartmannsgruber, Willm-Thomas Heyken, Michael Kacik, Anuradha Kaistha, Ivica Grgic, Christian Harteneck, Wolfgang Liedtke, Joachim Hoyer, Ralf Köhler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1959246?pdf=render