Arterial response to shear stress critically depends on endothelial TRPV4 expression.
BACKGROUND: In blood vessels, the endothelium is a crucial signal transduction interface in control of vascular tone and blood pressure to ensure energy and oxygen supply according to the organs' needs. In response to vasoactive factors and to shear stress elicited by blood flow, the endotheliu...
Main Authors: | Veronika Hartmannsgruber, Willm-Thomas Heyken, Michael Kacik, Anuradha Kaistha, Ivica Grgic, Christian Harteneck, Wolfgang Liedtke, Joachim Hoyer, Ralf Köhler |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC1959246?pdf=render |
Similar Items
-
Downregulation of miR-503 in Activated Kidney Fibroblasts Disinhibits KCNN4 in an in Vitro Model of Kidney Fibrosis
by: Christoph Mann, et al.
Published: (2019-02-01) -
Endothelial pannexin 1–TRPV4 channel signaling lowers pulmonary arterial pressure in mice
by: Zdravka Daneva, et al.
Published: (2021-09-01) -
THE DIFFERENTIAL EXPRESSION OF TRPV1 IN PULMONARY ARTERY SMOOTH MUSCLE CELLS AND PULMONARY ENDOTHELIAL CELLS
by: DASH, SWETALEENA
Published: (2016) -
NF-κB Pathway as a Potential Target for Treatment of Critical Stage COVID-19 Patients
by: Ralf Kircheis, et al.
Published: (2020-12-01) -
TRPV Subfamily (TRPV2, TRPV3, TRPV4, TRPV5, and TRPV6) Gene and Protein Expression in Patients with Ulcerative Colitis
by: Joel J. Toledo Mauriño, et al.
Published: (2020-01-01)