Proteolytic processing of the L-type Ca2+ channel alpha11.2 subunit in neurons [version 2; referees: 3 approved]

Background: The L-type Ca2+ channel Cav1.2 is a prominent regulator of neuronal excitability, synaptic plasticity, and gene expression. The central element of Cav1.2 is the pore-forming α11.2 subunit. It exists in two major size forms, whose molecular masses have proven difficult to precisely determ...

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Bibliographic Details
Main Authors: Olivia R. Buonarati, Peter B. Henderson, Geoffrey G. Murphy, Mary C. Horne, Johannes W. Hell
Format: Article
Language:English
Published: F1000 Research Ltd 2018-08-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-1166/v2