Rab26 suppresses migration and invasion of breast cancer cells through mediating autophagic degradation of phosphorylated Src

Abstract Rab proteins play crucial roles in membrane trafficking. Some Rab proteins are implicated in cancer development through regulating protein sorting or degradation. In this study, we found that the expression of Rab26 is suppressed in the aggressive breast cancer cells as compared to the leve...

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Bibliographic Details
Main Authors: Huiying Liu, Yuxia Zhou, Hantian Qiu, Ruijuan Zhuang, Yang Han, Xiaoqing Liu, Xi Qiu, Ziyan Wang, Liju Xu, Ran Tan, Wanjin Hong, Tuanlao Wang
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03561-7