ABO blood groups influence macrophage-mediated phagocytosis of Plasmodium falciparum-infected erythrocytes.

Erythrocyte polymorphisms associated with a survival advantage to Plasmodium falciparum infection have undergone positive selection. There is a predominance of blood group O in malaria-endemic regions, and several lines of evidence suggest that ABO blood groups may influence the outcome of P. falcip...

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Bibliographic Details
Main Authors: Kayla T Wolofsky, Kodjo Ayi, Donald R Branch, Annika K Hult, Martin L Olsson, W Conrad Liles, Christine M Cserti-Gazdewich, Kevin C Kain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3469569?pdf=render