Diabetic HDL is dysfunctional in stimulating endothelial cell migration and proliferation due to down regulation of SR-BI expression.

Diabetic HDL had diminished capacity to stimulate endothelial cell (EC) proliferation, migration, and adhesion to extracellular matrix. The mechanism of such dysfunction is poorly understood and we therefore sought to determine the mechanistic features of diabetic HDL dysfunction.We found that the d...

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Bibliographic Details
Main Authors: Bing Pan, Yijing Ma, Hui Ren, Yubin He, Yongyu Wang, Xiaofeng Lv, Donghui Liu, Liang Ji, Baoqi Yu, Yuhui Wang, Y Eugene Chen, Subramaniam Pennathur, Jonathan D Smith, George Liu, Lemin Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3487724?pdf=render