Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells

Summary: The process of hematopoiesis is subject to substantial ontogenic remodeling that is accompanied by alterations in cellular fate during both development and disease. We combine state-of-the-art mass spectrometry with extensive functional assays to gain insight into ontogeny-specific proteomi...

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Bibliographic Details
Main Authors: Maria Jassinskaja, Kristýna Pimková, Nejc Arh, Emil Johansson, Mina Davoudi, Carlos-Filipe Pereira, Ewa Sitnicka, Jenny Hansson
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721002084