Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery.

INTRODUCTION:Post-operative infections occur frequently following major surgery. The magnitude of the post-operative immune response is associated with an increased risk of post-operative infections, although the mechanisms driving post-operative immune-dysfunction and the potential reversibility of...

Full description

Bibliographic Details
Main Authors: Hew D T Torrance, E Rebecca Longbottom, Mark E Vivian, Bagrat Lalabekyan, Tom E F Abbott, Gareth L Ackland, Charles J Hinds, Rupert M Pearse, Michael J O'Dwyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6136775?pdf=render