D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway

D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway

Abstract This study was designed to explore the protective effect of D4F, an apolipoprotein A-I mimetic peptide, on nuclear factor-κB (NF-κB)-dependent Fas/Fas ligand (FasL) pathway-mediated apoptosis in macrophages induced by oxidized low-density lipoprotein (ox-LDL). Our results showed that ox-LDL...

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Bibliographic Details
Main Authors: Hua Tian, Shu-tong Yao, Na-na Yang, Jie Ren, Peng Jiao, Xiangjian Zhang, Dong-xuan Li, Gong-an Zhang, Zhen-fang Xia, Shu-cun Qin
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07656-0

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https://doi.org/10.1038/s41598-017-07656-0

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