Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose.

Dietary macronutrient composition alters metabolism through several mechanisms, including post-translational modification (PTM) of proteins. To connect diet and molecular changes, here we performed short- and long-term feeding of mice with standard chow diet (SCD) and high-fat diet (HFD), with or wi...

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Bibliographic Details
Main Authors: Jesse G Meyer, Samir Softic, Nathan Basisty, Matthew J Rardin, Eric Verdin, Bradford W Gibson, Olga Ilkayeva, Christopher B Newgard, C Ronald Kahn, Birgit Schilling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0208973