Genotoxic risk in humans and acute toxicity in rats of a novel oral high-dose coenzyme Q10 oleogel

Coenzyme Q10 (CoQ10) supplementation has demonstrated to be safe and effective in primary and secondary CoQ10 deficiencies. Previously, we have designed a high-dose CoQ10 oleogel (1 g/disk) with excipients used in quantities that do not represent any toxic risk. However, it was necessary to demonstr...

Full description

Bibliographic Details
Main Authors: Natalia Ehrenhaus Masotta, Fabian Martinez-Perafan, Marta Ana Carballo, Susana Beatriz Gorzalczany, Ana M. Rojas, Valeria P. Tripodi
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750021001165