Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases

Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases

Abstract Non-small cell lung cancer (NSCLC) brain metastasis cell lines and in vivo models are not widely accessible. Herein we report on a direct-from patient-derived xenograft (PDX) model system of NSCLC brain metastases with genomic annotation useful for translational and mechanistic studies. Bot...

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Bibliographic Details
Main Authors: Andrew M. Baschnagel, Saakshi Kaushik, Arda Durmaz, Steve Goldstein, Irene M. Ong, Lindsey Abel, Paul A. Clark, Zafer Gurel, Ticiana Leal, Darya Buehler, Gopal Iyer, Jacob G. Scott, Randall J. Kimple
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81832-1

Internet

https://doi.org/10.1038/s41598-021-81832-1

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