Functional maps of protein complexes from quantitative genetic interaction data.

Recently, a number of advanced screening technologies have allowed for the comprehensive quantification of aggravating and alleviating genetic interactions among gene pairs. In parallel, TAP-MS studies (tandem affinity purification followed by mass spectroscopy) have been successful at identifying p...

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Bibliographic Details
Main Authors: Sourav Bandyopadhyay, Ryan Kelley, Nevan J Krogan, Trey Ideker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2289880?pdf=render