CSF evidence of pericyte damage in Alzheimer’s disease is associated with markers of blood-brain barrier dysfunction and disease pathology

CSF evidence of pericyte damage in Alzheimer’s disease is associated with markers of blood-brain barrier dysfunction and disease pathology

Abstract Background We aimed to assess the relationship between levels of a cerebrospinal fluid (CSF) marker of pericyte damage, soluble platelet-derived growth factor receptor β (sPDGFRβ) and CSF markers of blood-brain barrier (BBB) integrity (CSF albumin and CSF/serum albumin ratio) and disease pa...

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Bibliographic Details
Main Authors: J. S. Miners, P. G. Kehoe, S. Love, H. Zetterberg, K. Blennow
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Alzheimer’s Research & Therapy
Subjects:
Platelet-derived growth factor receptor β
PDGFRβ
Cerebrospinal fluid
CSF
CSF albumin
Alzheimer’s disease
Online Access:http://link.springer.com/article/10.1186/s13195-019-0534-8

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http://link.springer.com/article/10.1186/s13195-019-0534-8

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