Combined patterns of IGHV repertoire and cytogenetic/molecular alterations in monoclonal B lymphocytosis versus chronic lymphocytic leukemia.

Combined patterns of IGHV repertoire and cytogenetic/molecular alterations in monoclonal B lymphocytosis versus chronic lymphocytic leukemia.

BACKGROUND: Chronic lymphocytic leukemia (CLL)-like monoclonal B lymphocytosis (MBL) with (MBL(hi)) or without (MBL(lo)) absolute B-lymphocytosis precedes most CLL cases,the specific determinants for malignant progression remaining unknown. METHODOLOGY/PRINCIPAL FINDINGS: For this purpose, simultane...

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Main Authors: Ana Henriques, Arancha Rodríguez-Caballero, Wendy G Nieto, Anton W Langerak, Ignacio Criado, Quentin Lécrevisse, Marcos González, Maria L Pais, Artur Paiva, Julia Almeida, Alberto Orfao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3701012?pdf=render

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http://europepmc.org/articles/PMC3701012?pdf=render

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