Whole Exome Sequencing of Biliary Tubulopapillary Neoplasms Reveals Common Mutations in Chromatin Remodeling Genes

Whole Exome Sequencing of Biliary Tubulopapillary Neoplasms Reveals Common Mutations in Chromatin Remodeling Genes

The molecular carcinogenesis of intraductal tubulopapillary neoplasms (ITPN), recently described as rare neoplasms in the pancreato-biliary tract with a favorable prognosis despite a high incidence of associated pancreato-biliary adenocarcinoma, is still poorly understood. To identify driver genes,...

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Bibliographic Details
Main Authors: Claudia Gross, Thomas Engleitner, Sebastian Lange, Julia Weber, Moritz Jesinghaus, Björn Konukiewitz, Alexander Muckenhuber, Katja Steiger, Nicole Pfarr, Benjamin Goeppert, Gisela Keller, Wilko Weichert, Nazmi Volkan Adsay, Günter Klöppel, Roland Rad, Irene Esposito, Anna Melissa Schlitter
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
pancreas
bile duct
intraductal tubulopapillary neoplasms
whole exome sequencing
chromatin remodeling genes
Online Access:https://www.mdpi.com/2072-6694/13/11/2742

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https://www.mdpi.com/2072-6694/13/11/2742

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