Genetically Engineered Mouse Models of Liver Tumorigenesis Reveal a Wide Histological Spectrum of Neoplastic and Non-Neoplastic Liver Lesions

Genetically Engineered Mouse Models of Liver Tumorigenesis Reveal a Wide Histological Spectrum of Neoplastic and Non-Neoplastic Liver Lesions

Genetically engineered mouse models (GEMM) are an elegant tool to study liver carcinogenesis in vivo. Newly designed mouse models need detailed (histopathological) phenotyping when described for the first time to avoid misinterpretation and misconclusions. Many chemically induced models for hepatoca...

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Bibliographic Details
Main Authors: Katja Steiger, Nina Gross, Sebastian A. Widholz, Roland Rad, Wilko Weichert, Carolin Mogler
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
GEMM
liver tumorigenesis
liver lesions
histology
Online Access:https://www.mdpi.com/2072-6694/12/8/2265

Internet

https://www.mdpi.com/2072-6694/12/8/2265

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