Effect of Melittin on Metabolomic Profile and Cytokine Production in PMA-Differentiated THP-1 Cells

Melittin, the major active peptide of honeybee venom (BV), has potential for use in adjuvant immunotherapy. The immune system response to different stimuli depends on the secretion of different metabolites from macrophages. One potent stimulus is lipopolysaccharide (LPS), a component isolated from g...

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Bibliographic Details
Main Authors: Abdulmalik M. Alqarni, Valerie A. Ferro, John A. Parkinson, Mark J. Dufton, David G. Watson
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Vaccines
Subjects:
Online Access:http://www.mdpi.com/2076-393X/6/4/72