Operationalisation of the Randomized Embedded Multifactorial Adaptive Platform for COVID-19 trials in a low and lower-middle income critical care learning health system. [version 1; peer review: 2 approved]

The Randomized Embedded Multifactorial Adaptive Platform (REMAP-CAP) adapted for COVID-19) trial is a global adaptive platform trial of hospitalised patients with COVID-19. We describe implementation in three countries under the umbrella of the Wellcome supported Low and Middle Income Country (LMIC)...

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Main Authors: Diptesh Aryal, Abi Beane, Arjen M. Dondorp, Cameron Green, Rashan Haniffa, Madiha Hashmi, Devachandran Jayakumar, John C. Marshall, Colin J. McArthur, Srinivas Murthy, Steven A. Webb, Subhash P. Acharya, Pramodya G. P. Ishani, Issrah Jawad, Sushil Khanal, Kanchan Koirala, Subekshya Luitel, Upulee Pabasara, Hem Raj Paneru, Ashok Kumar, Shoaib Siddiq Patel, Nagarajan Ramakrishnan, Nawal Salahuddin, Mohiuddin Shaikh, Timo Tolppa, Ishara Udayanga, Zulfiqar Umrani
Format: Article
Language:English
Published: Wellcome 2021-01-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/6-14/v1