An epigenetic switch involving overlapping fur and DNA methylation optimizes expression of a type VI secretion gene cluster.
Type VI secretion systems (T6SS) are macromolecular machines of the cell envelope of Gram-negative bacteria responsible for bacterial killing and/or virulence towards different host cells. Here, we characterized the regulatory mechanism underlying expression of the enteroagregative Escherichia coli...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-07-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3145626?pdf=render |