Neprilysin inhibition does not alter dynamic of proenkephalin‐A 119‐159 and pro‐substance P in heart failure

Neprilysin inhibition does not alter dynamic of proenkephalin‐A 119‐159 and pro‐substance P in heart failure

Abstract Aims As NEP degrades many substrates, the specific therapeutic mechanism of NEP inhibition with angiotensin receptor neprilysin inhibitor (ARNi) in heart failure with reduced ejection fraction (HFrEF) is not entirely evident. The aim of this study was to investigate the response of two subs...

Full description

Bibliographic Details
Main Authors: Henrike Arfsten, Georg Goliasch, Philipp E. Bartko, Suriya Prausmüller, Georg Spinka, Anna Cho, Johannes Novak, Julia Mascherbauer, Helmuth Haslacher, Guido Strunk, Martin Hülsmann, Noemi Pavo
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:ESC Heart Failure
Subjects:
Neprilysin
Substance P
Enkephalin
ARNi
Heart failure
Online Access:https://doi.org/10.1002/ehf2.13278

Internet

https://doi.org/10.1002/ehf2.13278

Similar Items